It is one of three changes made by manager Michael Carrick, with Lisandro Martinez and Matheus Cunha also brought into the starting XI.
Ayden Heaven, Mason Mount and Youri Tielemans are among the substitutes, while Kobbie Mainoo is also on the bench after missing United’s last four games through injury.
Estevao comes in for his first Premier League start of the season, as Xabi Alonso makes four changes to the Chelsea XI that started Wednesday’s EFL Cup loss at Liverpool.
Malo Gusto and Danny Welbeck drop to the bench, Maxence Lacroix is out with a hamstring injury and Jordan Henderson is a surprise absentee from the squad.
Chelsea XI: Penders; Acheampong, Fofana, Colwill, Palestra; Caicedo, Lavia; Estevao, Palmer, Neto; Rogers.
Subs: Sharman-Lowe, Barco, Welbeck, Emegha, Quenda, Gusto, Chavarria, Nicoll-Jazuli, Subuloye.
Manchester United XI: Lammens; Yoro, Maguire, Martinez, Dalot; Santos, Baleba; Amad, Fernandes, Cunha; Mbeumo.
Subs: Darlow, Mazraoui, De Ligt, Mount, Zirkzee, Tielemans, Heaven, Lacey, Mainoo.
